Prof. Xie's research interests include VLSI Design, Electronics Design Automation, Computer Architecture, Embedded Systems Design. Specifically, recent research projects he has been involved include EDA tools and architectures for 3D IC design, embedded system synthesis, low power and thermal-aware techniques, robust design techniques related to soft errors and process variation.

His research is supported by NSF, DARPA, SRC, IBM, The Technology Collaborative, Honda, Toyota, Qualcomm, ITRI